Selective laser melting, as an additive manufacturing technology for direct manufacturing of precise metal parts, can make complex functional parts directly. In order to meet the requirement of personalized medical parts for individual geometry and good biological performance, the selective laser melting (SLM) equipments, DiMetal series, are used to develop its applications by biomedical metallic materials, such as 316L stainless steel, CoCrMo, Ti6Al4V. Moreover, the fabricating density, the fabricating mechanical properties of related materials, and the processability of geometry during SLM process are studied. Personalized dental crown, lingual orthodontic brackets, surgical guides, total knee replacement femur prosthesis, proximal femoral prosthesis, and repair skull body are customized designed and manufactured by the DiMetal series equipments. The research and results demonstrate that the Dimetal series SLM equipments and additive manufacturing process for above materials could be applied in rapidmanufacturing of personalized medical parts, which provides a new way for rapid responding to personalized medical parts’ design andmanufacture.